Abstract

Aim: Studies on thirdhand smoke (THS) have been steadily increasing in the literature. This study aimed to examine the scientific development of the THS concept, as well as the prominent authors, journals, and research trends.

Methods: This bibliometric study was conducted using the Web of Science Core Collection database. The search strategy included the combinations: “third hand smoking,” “thirdhand smoking,” “third-hand smoking,” “thirdhand smoke,” “third-hand smoke,” and “third hand smoke.” Only articles and review articles written in English were included. A total of 316 publications on THS, authored by 251 researchers from 43 countries, were identified between 2009 and 2025. Data were analyzed and visualized using VOSviewer.

Results: The concept first appeared in 2009. The highest number of publications was in 2021 (n = 41), while the lowest was in 2009 (n = 2). These publications received 6888 citations in total, excluding 4529 self-citations. The average number of citations per publication was 21,8, with an H-index of 41. Nicotine & Tobacco Research published the most THS-related articles (n = 19), whereas Tobacco Control was the most cited journal (n = 105; TLS = 4343). The United States, China, and Türkiye were the leading contributors. The most cited author was Matt, G.E. (n = 92; TLS = 3385). Common keywords co-occurring with THS included “tobacco”, “secondhand smoke”, “passive smoking”, “oxidative stress” and “smoking”.

Conclusion: Research on THS has grown significantly over the past 15 years. It is recommended that future studies on tobacco control address the concept of thirdhand smoke.

Keywords: smoke, tobacco, tobacco smoke pollution, third hand smoke

References

  1. U.S. Department of Health and Human Services. Smoking and health: a report of surgeon general. U.S.: U.S. Department of Health Education and Welfare; 1964.
  2. U.S. Department of Health and Human Services. The health consequences of involuntary smoking: a report of the surgeon general. U.S.: Office on Smoking and Health; 1986.
  3. U.S. Department of Health and Human Services. The health consequences of involuntary exposure to tobacco smoke: a report of the surgeon general. Atlanta (GA): Centers for Disease Control and Prevention; 2006.
  4. Winickoff JP, Friebely J, Tanski SE, et al. Beliefs about the health effects of “thirdhand” smoke and home smoking bans. Pediatrics 2009; 123: e74-e79. https://doi.org/10.1542/peds.2008-2184
  5. Becquemin MH, Bertholon JF, Bentayeb M, et al. Third-hand smoking: indoor measurements of concentration and sizes of cigarette smoke particles after resuspension. Tob Control 2010; 19: 347-348. https://doi.org/10.1136/tc.2009.034694
  6. Sleiman M, Gundel LA, Pankow JF, Jacob P, Singer BC, Destaillats H. Formation of carcinogens indoors by surface-mediated reactions of nicotine with nitrous acid, leading to potential thirdhand smoke hazards. Proc Natl Acad Sci U S A 2010; 107: 6576-6581. https://doi.org/10.1073/pnas.0912820107
  7. Ramírez N, Vallecillos L, Lewis AC, Borrull F, Marcé RM, Hamilton JF. Comparative study of comprehensive gas chromatography-nitrogen chemiluminescence detection and gas chromatography-ion trap-tandem mass spectrometry for determining nicotine and carcinogen organic nitrogen compounds in thirdhand tobacco smoke. J Chromatogr A 2015; 1426: 191-200. https://doi.org/10.1016/j.chroma.2015.11.035
  8. Yao T, Lea Watkins S, Sung HY, et al. Association between tobacco product use and respiratory health and asthma-related interference with activities among U.S. Adolescents. Prev Med Rep 2024; 41: 102712. https://doi.org/10.1016/j.pmedr.2024.102712
  9. Kolci K, Nur Garipkuş S, Reis R, et al. Thirdhand smoke exposure and its toxicological impacts: a review on target organ based studies. J Pharm Sci 2023; 48: 303-318. doi:10.55262/fabadeczacilik.1144926
  10. Ahialey JK, Lee Y, Park MB, Huh J. Trends in academic research on thirdhand smoke using bibliometric analysis. Tob Induc Dis 2025; 23: 10.18332/tid/201402. https://doi.org/10.18332/tid/201402
  11. Matt GE, Quintana PJE, Destaillats H, et al. Thirdhand tobacco smoke: emerging evidence and arguments for a multidisciplinary research agenda. Environ Health Perspect 2011; 119: 1218-1226. https://doi.org/10.1289/ehp.1103500
  12. Matt GE, Quintana PJE, Zakarian JM, et al. When smokers move out and non-smokers move in: residential thirdhand smoke pollution and exposure. Tob Control 2011; 20: e1. https://doi.org/10.1136/tc.2010.037382
  13. Wilson KM, Klein JD, Blumkin AK, Gottlieb M, Winickoff JP. Tobacco-smoke exposure in children who live in multiunit housing. Pediatrics 2011; 127: 85-92. https://doi.org/10.1542/peds.2010-2046
  14. Soleimani F, Dobaradaran S, De-la-Torre GE, Schmidt TC, Saeedi R. Content of toxic components of cigarette, cigarette smoke vs cigarette butts: a comprehensive systematic review. Sci Total Environ 2022; 813: 152667. https://doi.org/10.1016/j.scitotenv.2021.152667
  15. Crotty Alexander LE, Shin S, Hwang JH. Inflammatory diseases of the lung induced by conventional cigarette smoke: a review. Chest 2015; 148: 1307-1322. https://doi.org/10.1378/chest.15-0409
  16. Matt GE, Hoh E, Quintana PJE, Zakarian JM, Arceo J. Cotton pillows: a novel field method for assessment of thirdhand smoke pollution. Environ Res 2019; 168: 206-210. https://doi.org/10.1016/j.envres.2018.09.025
  17. Matt GE, Greiner L, Record RA, et al. Policy-relevant differences between secondhand and thirdhand smoke: strengthening protections from involuntary exposure to tobacco smoke pollutants. Tob Control 2024; 33: 798-806. https://doi.org/10.1136/tc-2023-057971
  18. Matt GE, Mahabee-Gittens EM, Zakarian JM, Quintana PJE, Hoh E, Myers M. Nicotine in thirdhand smoke residue predicts relapse from smoking cessation: a pilot study. Addict Behav 2019; 98: 106041. https://doi.org/10.1016/j.addbeh.2019.106041
  19. Matt GE, Merianos AL, Quintana PJE, Hoh E, Dodder NG, Mahabee-Gittens EM. Prevalence and income-related disparities in thirdhand smoke exposure to children. JAMA Netw Open 2022; 5: e2147184. https://doi.org/10.1001/jamanetworkopen.2021.47184
  20. Sleiman M, Logue JM, Luo W, Pankow JF, Gundel LA, Destaillats H. Inhalable constituents of thirdhand tobacco smoke: chemical characterization and health impact considerations. Environ Sci Technol 2014; 48: 13093-13101. https://doi.org/10.1021/es5036333
  21. Hang B, Wang P, Zhao Y, Chang H, Mao JH, Snijders AM. Thirdhand smoke: Genotoxicity and carcinogenic potential. Chronic Dis Transl Med 2019; 6: 27-34. https://doi.org/10.1016/j.cdtm.2019.08.002
  22. Hang B, Wang Y, Huang Y, et al. Short-term early exposure to thirdhand cigarette smoke increases lung cancer incidence in mice. Clin Sci (Lond) 2018; 132: 475-488. https://doi.org/10.1042/CS20171521
  23. Torres S, Merino C, Paton B, Correig X, Ramírez N. Biomarkers of exposure to secondhand and thirdhand tobacco smoke: recent advances and future perspectives. Int J Environ Res Public Health 2018; 15: 2693. https://doi.org/10.3390/ijerph15122693
  24. Mahabee-Gittens EM, Quintana PJE, Hoh E, et al. Collecting hand wipe samples to assess thirdhand smoke exposure. Front Public Health 2021; 9: 770505. https://doi.org/10.3389/fpubh.2021.770505
  25. Antonucci A, Andreoli R, Maccari C, Vitali M, Protano C. Effects of environmental tobacco smoke on oxidative stress in childhood: a human biomonitoring study. Toxics 2024; 12: 557. https://doi.org/10.3390/toxics12080557

How to cite

Odacı, N., & Çürük, M. N. (2025). Bibliometric analysis of studies on the concept of third-hand smoke. Turkish Journal of Tobacco Control, 1-10. https://doi.org/10.64511/TJTC.2025.25